Advertisement

Topics

Taylor Dispersion of Polydisperse Nanoclusters and Nanoparticles: Modelling, Simulation and Analysis.

07:00 EST 8th March 2018 | BioPortfolio

Summary of "Taylor Dispersion of Polydisperse Nanoclusters and Nanoparticles: Modelling, Simulation and Analysis."

The dimensions of ultra-small inorganic nanoparticles (US-NPs) is in the heart of the design of diagnostic and therapeutic efficacy; yet its accurate measurement is challenging for most experimental techniques. We show here how to design and analyze Taylor dispersion experiments to characterize the two most sought-after parameters describing size distributions: the number-averaged mean size and polydispersity index. To demonstrate the power of the method, we simulated and analyzed taylograms corresponding to gold US-NPs distributed normally. By using simulation and including experimental noise, we had the advantage that the true values describing size distribution were known exactly, and thus, we were able test the abso-lute accuracy of our analysis and its robustness against noise. Theory and computational experiments were found in very good agreement, providing a significant step in the analysis of ultra-small inorganic nanoparticles and Taylor dispersion experiments.

Affiliation

Journal Details

This article was published in the following journal.

Name: Analytical chemistry
ISSN: 1520-6882
Pages:

Links

DeepDyve research library

PubMed Articles [18545 Associated PubMed Articles listed on BioPortfolio]

Nanoparticles Organization Controls Their Potency as Universal Glues for Gels.

Nanoparticles have been recently shown to act as universal glues for both synthetic and biological gels, providing a tuneable, cheap and general solution to the centuries-old problem of sticking soft ...

A comparison of two biorelevant in vitro drug release methods for nanotherapeutics based on advanced physiologically-based pharmacokinetic modelling.

As a growing number of nanotherapeutics enters the market, improved analytical techniques for measuring the drug release are required. Biorelevant release tests have become a standard in the predictio...

Generalized dispersion analysis of crystals with unknown symmetry and orientation.

With generalized dispersion analysis it is possible to gain the dispersion parameters and dielectric tensor function of crystals with not only unknown orientation of the symmetry elements in within th...

Performance analysis of triple asymmetrical optical multiple ring resonator with a 1 × 3 input-output waveguide for application as an optical filter.

Modelling of a triple asymmetrical optical multiple ring resonator (TAOMRR) with a 1×3 input-output waveguide has been carried out in the present paper, and its performance as an optical filter is an...

Modelling the dispersion of radon-222 from a landform covered by low uranium grade waste rock.

The dispersion of Rn from the planned remediation of the Ranger U mine in the wet-dry tropics of Northern Australia was modelled. Dry and wet season contour maps of Rn dose normalised to Ra activity c...

Clinical Trials [2158 Associated Clinical Trials listed on BioPortfolio]

Evaluation of Image-Based Modelling on Clinical Decisions in Coarctation of the Aorta

To answer the research question: "Would image-based modelling result in different clinical decisions as compared to clinical practice guidelines?", we will conduct a randomized controlled ...

Topical Application of Silver Nanoparticles and Oral Pathogens in Ill Patients

The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.

Analysis of the Stress Induced by in Situ Simulation

Vulnerability to psychologic distress induced by in situ simulation. Objectives: Psychological evaluation at short and long term on working satisfaction, mental health, and acute stress a...

French Survey About Student's Sleep Perturbations Before Simulation Session.

High fidelity simulation provide educational skills but the simulation of critical events could eventually provide anxiety among participants. The anxiety could raise before the simulatio...

Reamed Nailing Versus Taylor Spatial Frame in Tibia Shaft Fractures

This is a randomised, bi-centre, prospective, clinical trial in patients with closed tibia shaft fractures. The fracture should be fresh/acute and seen within 3 weeks after the injury. Pat...

Medical and Biotech [MESH] Definitions

Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.

A computer simulation technique that is used to model the interaction between two molecules. Typically the docking simulation measures the interactions of a small molecule or ligand with a part of a larger molecule such as a protein.

A computer simulation developed to study the motion of molecules over a period of time.

The method of measuring the dispersion of an optically active molecule to determine the relative magnitude of right- or left-handed components and sometimes structural features of the molecule.

Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

Cardiovascular disease (CVD)
Acute Coronary Syndromes (ACS) Blood Cardiovascular Dialysis Hypertension Stent Stroke Vascular Cardiovascular disease (CVD) includes all the diseases of the heart and circulation including coronary heart disease (angina...

Collaborations in biotechnology
Commercial and academic collaborations are used throughout the biotechnology and pharmaceutical sector to enhance research and product development. Collaborations can take the form of research and evaluation agreements, licensing, partnerships etc. ...


Searches Linking to this Article