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The impact of single-cell RNA sequencing on understanding the functional organization of the immune system.

08:00 EDT 14th March 2018 | BioPortfolio

Summary of "The impact of single-cell RNA sequencing on understanding the functional organization of the immune system."

Application of single-cell genomics technologies has revolutionized our approach to study the immune system. Unravelling the functional diversity of immune cells and their coordinated response is key to understanding immunity. Single-cell transcriptomics technologies provide high-dimensional assessment of the transcriptional states of immune cells and have been successfully applied to discover new immune cell types, reveal haematopoietic lineages, identify gene modules dictating immune responses and investigate lymphocyte antigen receptor diversity. In this review, we discuss the impact and applications of single-cell RNA sequencing technologies in immunology.

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This article was published in the following journal.

Name: Briefings in functional genomics
ISSN: 2041-2657
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