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Genome-Wide Mapping of Protein-DNA Interactions on Nascent Chromatin.

07:00 EST 1st January 2018 | BioPortfolio

Summary of "Genome-Wide Mapping of Protein-DNA Interactions on Nascent Chromatin."

Chromatin immunoprecipitation (ChIP) is the most widely used method to analyze protein-DNA interactions in vivo. Coupled with next generation sequencing, ChIP-seq experiments map protein-DNA interactions in a genome-wide fashion. Here we describe a novel method called nasChIP-seq for mapping genome-wide occupancy of posttranslationally modified histones or transcription factors on newly replicated DNA.

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This article was published in the following journal.

Name: Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Pages: 231-238

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Medical and Biotech [MESH] Definitions

Methods used for studying the interactions of antibodies with specific regions of protein antigens. Important applications of epitope mapping are found within the area of immunochemistry.

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