Advertisement

Topics

A novel microsurgical rodent model for the transplantation of engineered cardiac muscle flap.

08:00 EDT 6th April 2018 | BioPortfolio

Summary of "A novel microsurgical rodent model for the transplantation of engineered cardiac muscle flap."

The survival of engineered cardiac muscle 'grafts' to the epicardium is limited by vascularization post-transplantation in rat models. In this article, we describe the methodology of a novel rat model that allows for the transplantation of an engineered cardiac muscle flap (ECMF) onto the epicardium.

Affiliation

Journal Details

This article was published in the following journal.

Name: Microsurgery
ISSN: 1098-2752
Pages:

Links

DeepDyve research library

PubMed Articles [19088 Associated PubMed Articles listed on BioPortfolio]

Innervation of an engineered muscle graft for reconstruction of muscle defects.

Autologous muscle flaps are commonly used to reconstruct defects that involve muscle impairment. In order to maintain viability and functionality of these flaps, they must be properly vascularized and...

CORM-401 reduces ischemia reperfusion injury in an ex vivo renal porcine model of the donation after cardiac death.

Carbon monoxide (CO) inhalation protects organ by reducing inflammation and cell death during transplantation processes in animal model. However, using CO in clinical transplantation is difficult due ...

THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION.

Heart transplantation is still the best therapeutic alternative for the treatment of end-stage heart failure. The use of criteria that consider the complications associated with this procedure can gua...

Personalized survival predictions via Trees of Predictors: An application to cardiac transplantation.

Risk prediction is crucial in many areas of medical practice, such as cardiac transplantation, but existing clinical risk-scoring methods have suboptimal performance. We develop a novel risk predictio...

Validation of a clinically-relevant rodent model of statin-associated muscle symptoms for use in pharmacological studies.

Various rodent models of statin-associated muscle symptoms (SAMS) have been used to investigate the aetiology of statin myotoxicity. Variability between these models, however, may be contributing to t...

Clinical Trials [10535 Associated Clinical Trials listed on BioPortfolio]

Autologous Cell-derived Tissue Engineered Cartilage for Repairing Articular Cartilage Lesions

This study is aimed at evaluating the feasibility and effectiveness of a completely natural tissue engineered cartilage, composed of a self-made tissue engineered oriented scaffold and aut...

A Pilot Study Investigating the Clinical Use of Tissue Engineered Vascular Grafts in Congenital Heart Surgery

An initial feasibility and safety study evaluating the use of autologous tissue engineered vascular grafts as extra cardiac total cavopulmonary connection (EC TCPC) conduits in children wi...

Testing the Re-Engineered Hospital Discharge

The purpose of this study is to determine if the "Re-Engineered Discharge" will decrease rehospitalization rates and adverse events of patients leaving Boston Medical Center.

Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model

The purpose of this study is to investigate and determine the time course and distribution on muscle hyperalgesia and muscle pain in a repeated, low dose NGF model. It is hypothesized that...

3D Tissue Engineered Bone Equivalent for Treatment of Traumatic Bone Defects

This study investigates safety and efficacy of traumatic bone defects treatment with use of 3D tissue engineered bone equivalent (3D-TEBE). The aim of this study is to evaluate 3D-TEBE tr...

Medical and Biotech [MESH] Definitions

Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.

An operation that uses stimulated latissimus dorsi muscle (SKELETAL MUSCLE VENTRICLE) to assist cardiac function. The latissimus dorsi muscle is mobilized from the chest wall and moved into the thorax through the bed of the resected 2nd or 3rd rib. The muscle is then wrapped around the left and right ventricles and stimulated to contract during cardiac systole by means of an implanted burst-stimulator. (Stedman, 26th ed)

Method of isolation and maintenance of a working heart for various cardiac measurements. The model allows for the separation of cardiac and systemic variables in the denervated heart.

Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).

One of two types of muscle in the body, characterized by the array of bands observed under microscope. Striated muscles can be divided into two subtypes: the CARDIAC MUSCLE and the SKELETAL MUSCLE.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

Transplantation
Organ transplantation is the moving of an organ from one body to another or from a donor site to another location on the patient's own body, for the purpose of replacing the recipient's damaged or absent organ. The emerging field of regenerative ...

Rheumatology
Arthritis Fibromyalgia Gout Lupus Rheumatic Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Diction...


Searches Linking to this Article