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Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing.

07:00 EST 29th January 2018 | BioPortfolio

Summary of "Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing."

Children requiring cortisol replacement therapy are often prescribed hydrocortisone doses of 2.5 mg, but as this is commercially unavailable 10 mg tablets, with functional break lines, are split commonly in an attempt to deliver the correct dose. This study aimed to determine the dose variation obtained from quartered hydrocortisone tablets when different operators performed the splitting procedure and to ascertain whether better uniformity could be attained from mini-tablets as an alternative formulation.

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This article was published in the following journal.

Name: BMJ paediatrics open
ISSN: 2399-9772
Pages: e000198

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Pediatrics
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...


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