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Follow-up and management of recurrent pregnancy losses due to massive perivillous fibrinoid deposition.

07:00 EST 1st March 2018 | BioPortfolio

Summary of "Follow-up and management of recurrent pregnancy losses due to massive perivillous fibrinoid deposition."

Massive perivillous fibrinoid deposition is a rare placental pathology associated with significant adverse pregnancy outcome and can recur. We provide a detailed case review of a woman through 10 of her pregnancies, including 8 consecutive pregnancy losses and 2 live births. We also conducted a retrospective chart review of all massive perivillous fibrinoid deposition placenta specimens at our institution over an eight-year period. A total of 42 cases of massive perivillous fibrinoid deposition were identified from 2007 to 2015, yielding an incidence of 0.16%. Recurrence was seen in subsequent pregnancy in eight out of nine (88.9%) cases with more than one specimen. The clinical characteristics, perinatal outcomes and α-feto protein level of the 42 cases are presented. Also, presented is a review of the literature discussing placental pathology, pathogenetic mechanisms and management of this condition.

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This article was published in the following journal.

Name: Obstetric medicine
ISSN: 1753-495X
Pages: 17-22

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Medical and Biotech [MESH] Definitions

The co-occurrence of pregnancy and NEOPLASMS. The neoplastic disease may precede or follow FERTILIZATION.

The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.

The co-occurrence of pregnancy and parasitic diseases. The parasitic infection may precede or follow FERTILIZATION.

The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.

Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.

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