Follow-up and management of recurrent pregnancy losses due to massive perivillous fibrinoid deposition.

07:00 EST 1st March 2018 | BioPortfolio

Summary of "Follow-up and management of recurrent pregnancy losses due to massive perivillous fibrinoid deposition."

Massive perivillous fibrinoid deposition is a rare placental pathology associated with significant adverse pregnancy outcome and can recur. We provide a detailed case review of a woman through 10 of her pregnancies, including 8 consecutive pregnancy losses and 2 live births. We also conducted a retrospective chart review of all massive perivillous fibrinoid deposition placenta specimens at our institution over an eight-year period. A total of 42 cases of massive perivillous fibrinoid deposition were identified from 2007 to 2015, yielding an incidence of 0.16%. Recurrence was seen in subsequent pregnancy in eight out of nine (88.9%) cases with more than one specimen. The clinical characteristics, perinatal outcomes and α-feto protein level of the 42 cases are presented. Also, presented is a review of the literature discussing placental pathology, pathogenetic mechanisms and management of this condition.


Journal Details

This article was published in the following journal.

Name: Obstetric medicine
ISSN: 1753-495X
Pages: 17-22


DeepDyve research library

PubMed Articles [14924 Associated PubMed Articles listed on BioPortfolio]

Inherited Thrombophilia and Pregnancy Complications: Should We Test?

Recurrent miscarriages and pregnancy-related complications cause significant stress to couples looking for successful pregnancy outcome as well as to health care professionals. There is conflicting ev...

Elevated percentage of CD3T cells and pregnancy outcome in women with recurrent pregnancy loss.

Even though the immune factor is not yet established as a cause of recurrent pregnancy loss (RPL), tons of other studies have shown that a significant proportion of immune abnormalities exist in RPL.

Acetylsalicylic acid does not prevent first trimester unexplained recurrent pregnancy loss: a randomized controlled trial.

Recurrent pregnancy loss occurs in about one percent of fertile couples. Without proper evidence for an effect different treatments have been used when no etiological factor has been detected. The pre...

Biochemical challenge: difficult management of recurrent hypoglycaemia in the setting of a massive solitary fibrous tumour of the liver.

Massive hemorrhage from a unique old cesarean scar ectopic pregnancy with negative urine and serum β-HCG: a rare case report.

Human chorionic gonadotropin (HCG) is an important indicator for the diagnosis of pregnancy. The authors report a unique case of cesarean scar ectopic pregnancy (CSEP) with negative urine and serum HC...

Clinical Trials [9967 Associated Clinical Trials listed on BioPortfolio]

Progesterone and Doppler in Recurrent Abortion

Recurrent pregnancy loss is classically defined as the occurrence of three or more consecutive pregnancy loss. The American Society of Reproductive Medicine has recently redefined recurren...

Study of the Role of Tissular Maternofetal Alloimmunization in Placentation Pathologies

Justification: We have recently demonstrated that maternofetal alloimmunization was not limited to blood cells: maternal alloimmunization against a glomerular podocyte antigen expressed b...

Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss

Recurrent pregnancy loss (RPL) defined as 3 or more pregnancy losses affects approximately 3% of couples trying to achieve parenthood. Most cases of RPL are unexplained and have no effecti...

Physical Examination-Indicated Pessary

Cervical insufficiency, previously referred to as cervical incompetence, has classically been defined as painless dilation of the cervix in the absence of contractions or bleeding in the s...

Recombinant Activated Factor VII in the Management of Massive Bleeding in Hospital Universiti Sains Malaysia

This is a retrospective descriptive study, to survey the treatment indications, transfusion need, coagulation profiles changes and clinical outcome of non-haemophiliac patients who receive...

Medical and Biotech [MESH] Definitions

The co-occurrence of pregnancy and NEOPLASMS. The neoplastic disease may precede or follow FERTILIZATION.

The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.

The co-occurrence of pregnancy and parasitic diseases. The parasitic infection may precede or follow FERTILIZATION.

The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.

Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.

Quick Search


DeepDyve research library

Relevant Topics

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

Obstetrics and gynaecology
Fertility Menopause Obstetrics & Gynaecology Osteoporosis Women's Health Obstetrics and gynaecology comprises the care of the pregnant woman, her unborn child and the management of diseases specific to women. Most consultant...

Searches Linking to this Article