Advertisement

Topics

Immune-cognitive system connectivity reduces bumblebee foraging success in complex multisensory floral environments.

08:00 EDT 13th April 2018 | BioPortfolio

Summary of "Immune-cognitive system connectivity reduces bumblebee foraging success in complex multisensory floral environments."

Bumblebees are declining at alarming rate worldwide, posing a significant threat to the function and diversity of temperate ecosystems. These declines have been attributed, in part, to the direct effect of specific pathogens on bumblebee survival. However, pathogens may also have a negative impact on host populations indirectly through immune-induced cognitive deficits in infected individuals. To gain greater insight into mechanisms and potential conservation implications of such 'immune-brain crosstalk' in bumblebees, we non-pathogenetically activated humoral and cellular immune pathways in individuals and then tested for long-term reductions in cognitive performance and foraging proficiency. We show that chronic activation of humoral, but not a cellular, immune pathways and effectors in foragers significantly reduces their ability to flexibly and efficiently harvest resources in multi-sensory floral environments for at least 7 days post-treatment. Humoral defense responses thus have the potential to confer significant foraging costs to bumblebee foragers over timeframes that would negatively impact colony growth and reproductive output under natural conditions. Our findings indicate that fitness effects of immune-brain crosstalk should be considered before attributing wild bumblebee decline to a particular pathogen species.

Affiliation

Journal Details

This article was published in the following journal.

Name: Scientific reports
ISSN: 2045-2322
Pages: 5953

Links

DeepDyve research library

PubMed Articles [20701 Associated PubMed Articles listed on BioPortfolio]

Aberrant memory system connectivity and working memory performance in subjective cognitive decline.

Subjective cognitive decline, a perceived worsening of cognitive functioning without objective deficit on assessment, could indicate incipient dementia. However, the neural correlates of subjective co...

Foraging Performance, Prosociality, and Kin Presence Do Not Predict Lifetime Reproductive Success in Batek Hunter-Gatherers.

Identifying the determinants of reproductive success in small-scale societies is critical for understanding how natural selection has shaped human evolution and behavior. The available evidence sugges...

Imidacloprid intensifies its impact on honeybee and bumblebee cellular immune response when challenged with LPS (lippopolysacharide) of Escherichia coli.

Insect hemocytes play an important role in insects' defense against environmental stressors as they are entirely dependent on their innate immune system for pathogen defense. In recent years a dramati...

An approach to directly link ICA and seed-based functional connectivity: Application to schizophrenia.

Independent component analysis (ICA) and seed-based analyses are widely used techniques for studying intrinsic neuronal activity in task-based or resting scans. In this work, we show there is a direct...

Brain networks of happiness: Dynamic functional connectivity among the default, cognitive and salience networks relates to subjective well-being.

Subjective well-being (SWB) reflects the cognitive and emotional evaluations of an individual's life and plays an important role in individual's success in health, work, and social relationships. Alth...

Clinical Trials [12884 Associated Clinical Trials listed on BioPortfolio]

Cognition and Functional Connectivity After Elective Treatment of Brain Aneurysms

The aim of this proposal is to investigate the effects of uneventful microsurgical and endovascular treatment of unruptured saccular non-giant anterior communicating artery [ACoA] aneurysm...

Functional MRI Changes Resulting From the Feuerstein Program in Older People With Mild Cognitive Impairment (MCI)

Background: The Feuerstein Instrumental Enrichment Program was designed to prevent mental deterioration and preserve cognitive abilities among people aged 60 and above. The program is an a...

Sleep Homeostasis in Primary Insomnia Following Behavioral Treatment

About 10% of the population is believed to suffer from Primary Insomnia. It is also believed that people with chronic insomnia have a sleep system that is essentially out of alignment (we...

A Combined Cell Therapy Approach to the Treatment of Neuroblastoma

This study adds an experimental treatment with another type of cells, called dendritic cells. It is hoped that these cells may stimulate the immune system to react against neuroblastoma in...

Cognitive Training in Stroke Patients

The study aims to investigate the behavioral effects, neural correlates and functional connectivity of cognitive training in patients with stroke

Medical and Biotech [MESH] Definitions

Success in bringing an effort to the desired end; the degree or level of success attained in some specified area (esp. scholastic) or in general.

The biochemical and electrophysiological interactions between the NERVOUS SYSTEM and IMMUNE SYSTEM that result in regulation of the immune system by the nervous system.

A cellular phone with advanced computing and connectivity capability built on an operating system.

Alteration of the immune system or of an immune response by agents that activate or suppress its function. This can include IMMUNIZATION or administration of immunomodulatory drugs. Immunomodulation can also encompass non-therapeutic alteration of the immune system effected by endogenous or exogenous substances.

Mechanisms of action and interactions of the components of the IMMUNE SYSTEM.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article