Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease.

08:00 EDT 7th May 2018 | BioPortfolio

Summary of "Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease."

Alzheimer's disease is a multifactorial disorder for which there is no disease-modifying treatment yet. CB2 receptors have emerged as a promising therapeutic target for Alzheimer's disease because they are expressed in neuronal and glial cells and their activation has no psychoactive effects.


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Name: CNS drugs
ISSN: 1179-1934


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Medical and Biotech [MESH] Definitions

A subclass of cannabinoid receptor found primarily on immune cells where it may play a role modulating release of CYTOKINES.

A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.

Compounds that inhibit or block the activity of CANNABINOID RECEPTORS.

Compounds that interact with and modulate the activity of CANNABINOID RECEPTORS.

Compounds that interact with and stimulate the activity of CANNABINOID RECEPTORS.

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