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Comparison of platelet rich plasma versus fibrin glue on colonic anastomoses in rats.

08:00 EDT 1st April 2018 | BioPortfolio

Summary of "Comparison of platelet rich plasma versus fibrin glue on colonic anastomoses in rats."

To compare platelet rich plasma (PRP) and fibrin glue about the effect of anastomotic healing.

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Journal Details

This article was published in the following journal.

Name: Acta cirurgica brasileira
ISSN: 1678-2674
Pages: 333-340

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Medical and Biotech [MESH] Definitions

A preparation consisting of PLATELETS concentrated in a limited volume of PLASMA. This is used in various surgical tissue regeneration procedures where the GROWTH FACTORS in the platelets enhance wound healing and regeneration.

The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.

A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.

Retraction of a clot resulting from contraction of PLATELET pseudopods attached to FIBRIN strands. The retraction is dependent on the contractile protein thrombosthenin. Clot retraction is used as a measure of platelet function.

The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.

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