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Overexpression of ABCB4 contributes to acquired doxorubicin resistance in breast cancer cells in vitro.

08:00 EDT 18th May 2018 | BioPortfolio

Summary of "Overexpression of ABCB4 contributes to acquired doxorubicin resistance in breast cancer cells in vitro."

Doxorubicin is one of the most active agents in the first-line therapy for metastatic breast cancer, but its utility is partially limited by the frequent emergence of doxorubicin resistance. In this study, we aimed to investigate the role of ATP-binding cassette sub-family B, member 4 (ABCB4) in acquired doxorubicin resistance in breast cancer cells, as well as its potential mechanism.

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Name: Cancer chemotherapy and pharmacology
ISSN: 1432-0843
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