Advertisement

Topics

Investigating common coding of observed and executed actions in the monkey brain using cross-modal multi-variate fMRI classification.

08:00 EDT 19th May 2018 | BioPortfolio

Summary of "Investigating common coding of observed and executed actions in the monkey brain using cross-modal multi-variate fMRI classification."

Mirror neurons are generally described as a neural substrate hosting shared representations of actions, by simulating or 'mirroring' the actions of others onto the observers' own motor system. Since single neuron recordings are rarely feasible in humans, it has been argued that cross-modal multi-variate pattern analysis (MVPA) of non-invasive fMRI data is a suitable technique to investigate common coding of observed and executed actions, allowing researchers to infer the presence of mirror neurons in the human brain. In an effort to close the gap between monkey electrophysiology and human fMRI data with respect to the mirror neuron system, here we tested this proposal for the first time in the monkey. Rhesus monkeys either performed reach-and-grasp or reach-and-touch motor acts with their right hand in the dark or observed videos of human actors performing similar motor acts. Unimodal decoding showed that both executed or observed motor acts could be decoded from numerous brain regions. Specific portions of rostral parietal, premotor and motor cortices, previously shown to house mirror neurons, in addition to somatosensory regions yielded significant asymmetric, action-specific cross-modal decoding. These results validate the use of cross-modal multi-variate fMRI analyses to probe the representations of own and others' actions in the primate brain and support the proposed mapping of others' actions onto the observer's own motor cortices.

Affiliation

Journal Details

This article was published in the following journal.

Name: NeuroImage
ISSN: 1095-9572
Pages:

Links

DeepDyve research library

PubMed Articles [15609 Associated PubMed Articles listed on BioPortfolio]

Motor simulation of multiple observed actions.

Research has shown that observed actions are represented in the motor system, leading to automatic imitative responses. However, in social life, we often see multiple persons acting together. Here, we...

Where and how our brain represents the temporal structure of observed action.

Reacting faster to the behaviour of others provides evolutionary advantages. Reacting to unpredictable events takes hundreds of milliseconds. Understanding where and how the brain represents what acti...

Distinct sensitivities of the lateral prefrontal cortex and extrastriate body area to contingency between executed and observed actions.

Detecting relationships between our own actions and the subsequent actions of others is critical for our social behavior. Self-actions differ from those of others in terms of action kinematics, body i...

CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms.

Monogenic mutations in the SHANK3 gene, which encodes a postsynaptic scaffold protein, play a causative role in autism spectrum disorder (ASD). Although a number of mouse models with Shank3 mutations ...

Attention orienting near the hand following performed and imagined actions.

Recent studies have documented that the hand's ability to perform actions affects the visual processing and attention for objects near the hand, suggesting that actions may have specific effects on vi...

Clinical Trials [7076 Associated Clinical Trials listed on BioPortfolio]

Observed Actions in Chronic Neck Pain

The aim of the present protocol is to prove if the observed actions (AOb) will improve the cervical range of motion (CROM) in patients with non-specific chronic neck pain (CNP). This study...

Evaluation of a Bio-inspired Coding Strategy for Cochlear Implant Users

This study will determine the facilitation, refractoriness and spatial spread effects of auditory nerve fiber responses to electrical stimulation via a cochlear implant. The performance o...

Investigating the Role of the Premotor Cortex in Higher Cognitive Functions

This project aims at understanding better the role of the frontal lobe of the brain in our capacity to perceive visual information consciously, and also, in our capacity to perceive others...

Inmediate Effect of the Visualization of Action

The observation of actions and motor imagery has demonstrated the activation of certain mechanisms similar to those that occur during active movement, which could induce immediate changes ...

Spider Phobia Opposite Action Treatment Study

This study tests the effectiveness of exposure therapy for fear of spiders as enhanced by the use of antagonistic or opposite actions during treatment. The goal of the study is to compare ...

Medical and Biotech [MESH] Definitions

A subfamily of the Old World monkeys, CERCOPITHECIDAE, that inhabits the forests of Africa and Asia. The genera COLOBUS (Procolobus; colobus), Nasalis (proboscis monkey), Presbytis (Semnopithecus; leaf monkey), Pygathrix (Rhinopithecus; snub-nosed monkey), and Simias (pig-tailed langur) all belong to this subfamily.

One of the four types of brain waves seen on EEG characterized by a high amplitude and a frequency of 4 Hz and below. They are considered the "deep sleep waves" observed during sleep in dreamless states, infancy, and in some brain disorders.

Neurons that fire when an animal acts or observes the same action of another thus coding the motor response. They were originally discovered in the premotor and parietal cortex of the monkey and studies have shown that neurons that have a similar mechanism are present in humans. Mirror neurons are theorized to be related to social cognition.

a genus of Old World monkeys of the family CERCOPITHECINAE that inhabit the forests and savannas of Africa. It contains only one species, ERYTHROCEBUS PATAS, also known as the patas monkey or red monkey.

A species of the genus ERYTHROCEBUS, subfamily CERCOPITHECINAE, family CERCOPITHECIDAE. It inhabits the flat open arid country of Africa. It is also known as the patas monkey or the red monkey.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article