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Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design.

08:00 EDT 30th May 2018 | BioPortfolio

Summary of "Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design."

Surgery and radiation therapy are the standard treatment options for meningiomas, but these treatments are not always feasible. Expression profiling was performed to determine the presence of therapeutic actionable biomarkers for prioritization and selection of agents.

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This article was published in the following journal.

Name: Journal of neuro-oncology
ISSN: 1573-7373
Pages:

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Medical and Biotech [MESH] Definitions

The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.

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A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.

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