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A 65-year-old patient with long-term metabolic syndrome and no relevant alcohol consumption was admitted to the hospital due to jaundice. His electronic record revealed a first suspicion of NAFLD 3 months ago because of slight alterations of LFT (AST 80 IU/L). Actual testing showed an important worsening of all LFT (AST 639 IU/L, ALT 456 IU/L, AP 248 IU/L, GGT 293 IU/L) with TB 23 mg/dl and an INR 1.22. This article is protected by copyright. All rights reserved.
This article was published in the following journal.
Name: Liver international : official journal of the International Association for the Study of the Liver
Acute liver failure of all causes is diagnosed in between 2000 and 2500 patients annually in the United States. Drug-induced acute liver failure is the leading cause of acute liver failure, accounting...
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Sudden liver failure in the presence of underlying compensated chronic LIVER DISEASE (e.g., LIVER CIRRHOSIS; HEPATITIS; and liver injury and failure) due to a precipitating acute hepatic insult.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
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A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment.
Hepatitis (plural hepatitides) is a medical condition defined by the inflammation of the liver and characterized by the presence of inflammatory cells in the tissue of the organ. The condition can be self-limiting (healing on its own) or can progress to ...