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Rapid and simple molecular tests for the detection of respiratory syncytial virus: a review.

08:00 EDT 11th June 2018 | BioPortfolio

Summary of "Rapid and simple molecular tests for the detection of respiratory syncytial virus: a review."

Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infections. The clinical manifestations of RSV are indistinguishable from other etiologies of acute respiratory infection. Therefore, accurate and timely laboratory testing is needed to impact clinical management. There are now multiple rapid, low-complexity, commercially available assays for RSV. These tests present significant performance advantages compared to older antigen detection tests. Accurate and rapid diagnosis of RSV has the potential for enabling timely cessation of unnecessary antibiotics and implementation of good infection control practices. Furthermore, a recently approved RSV diagnostic assay based on a novel nucleic acid amplification technology can reduce the test turnaround time to 13 minutes or less. Areas covered: The authors aim to review the importance of rapid and accurate testing for RSV and will describe the available molecular RSV diagnostic assays approved for use at the point-of-care. Expert commentary: Further independent evaluations are needed to confirm that the accuracy of the low-complexity assays is indeed similar to RT-PCR across the age spectrum, and in immunosuppressed hosts. In the future, the challenge will be to achieve a balance between increasingly sophisticated multiplex diagnostic platforms and tests that are sufficiently simple to be used at the point-of-care.

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This article was published in the following journal.

Name: Expert review of molecular diagnostics
ISSN: 1744-8352
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