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Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials.

08:00 EDT 11th June 2018 | BioPortfolio

Summary of "Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials."

Amantadine blocks N-methyl-D-aspartate (NMDA) receptors and has dopaminergic and noradrenergic action, a neurochemical profile that suggests its potential as an antidepressant drug. We conducted a systematic review of preclinical and clinical studies addressing the effects of amantadine in animal models of depression and in patients with depression.

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Journal Details

This article was published in the following journal.

Name: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
ISSN: 1809-452X
Pages:

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