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Spatial quantification of the synaptic activity phenotype across large populations of neurons with Markov random fields.

08:00 EDT 20th April 2018 | BioPortfolio

Summary of "Spatial quantification of the synaptic activity phenotype across large populations of neurons with Markov random fields."

The collective and coordinated synaptic activity of large neuronal populations is relevant to neuronal development as well as a range of neurological diseases. Quantification of synaptically-mediated neuronal signalling permits further downstream analysis as well as potential application in target validation and in vitro screening assays. Our aim is to develop a phenotypic quantification for neuronal activity imaging data of large populations of neurons, in particular relating to the spatial component of the activity.

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This article was published in the following journal.

Name: Bioinformatics (Oxford, England)
ISSN: 1367-4811
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