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Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer.

08:00 EDT 16th June 2018 | BioPortfolio

Summary of "Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer."

Paclitaxel-based chemoradiotherapy was proven to be efficacious in treating patients with advanced esophageal cancer. However, the toxicity and the development of resistance limited its anticancer efficiency. The present study was to evaluate the antitumor effects of lapatinib, a dual tyrosine inhibitor of both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), combined with paclitaxel on the esophageal squamous cancer.

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This article was published in the following journal.

Name: Cancer chemotherapy and pharmacology
ISSN: 1432-0843
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