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Use of polyvalent bacteriophages to combat biofilm of Proteus mirabilis causing catheter associated urinary tract infections.

08:00 EDT 20th June 2018 | BioPortfolio

Summary of "Use of polyvalent bacteriophages to combat biofilm of Proteus mirabilis causing catheter associated urinary tract infections."

Catheter-associated urinary tract infections (CAUTI) caused by Proteus mirabilis are very difficult to treat due to the ability of biofilm formation and drug resistance of these bacteria. The aim of this study was to assess the anti-biofilm activity of phages and develop phage cocktail to combat biofilm of P. mirabilis strains.

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This article was published in the following journal.

Name: Journal of applied microbiology
ISSN: 1365-2672
Pages:

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Genomic analyses of a novel bacteriophage (VB_PmiS-Isfahan) within Siphoviridae family infecting Proteus mirabilis.

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Medical and Biotech [MESH] Definitions

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that is frequently isolated from clinical specimens. Its most common site of infection is the urinary tract.

A plant genus of the family NYCTAGINACEAE. Members contain Mirabilis antiviral protein (a ribosome-inactivating protein).

A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the intestines of humans and a wide variety of animals, as well as in manure, soil, and polluted waters. Its species are pathogenic, causing urinary tract infections and are also considered secondary invaders, causing septic lesions at other sites of the body.

A COAGULASE-negative species of STAPHYLOCOCCUS found on the skin and MUCOUS MEMBRANE of warm-blooded animals. Similar to STAPHYLOCOCCUS EPIDERMIDIS and STAPHYLOCOCCUS HAEMOLYTICUS, it is a nosocomial pathogen in NICU settings. Subspecies include generally antibiotic susceptible and BIOFILM negative capitis and antibiotic resistant and biofilm positive urealyticus isolates.

Infections with bacteria of the genus PROTEUS.

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