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SPX-101 is stable in and retains function after exposure to cystic fibrosis sputum.

08:00 EDT 20th June 2018 | BioPortfolio

Summary of "SPX-101 is stable in and retains function after exposure to cystic fibrosis sputum."

In healthy lungs, epithelial sodium channel (ENaC) is regulated by short, palate, lung, and nasal clone 1 (SPLUNC1). In cystic fibrosis (CF), ENaC is hyperactivated in part due to a loss of SPLUNC1 function. We have developed SPX-101 to replace the lost function of SPLUNC1 in the CF lung.

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This article was published in the following journal.

Name: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
ISSN: 1873-5010
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