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Combination of checkpoint inhibitors with other agents as a strategy to improve anti-cancer effect - A glimpse to the future.

08:00 EDT 29th June 2018 | BioPortfolio

Summary of "Combination of checkpoint inhibitors with other agents as a strategy to improve anti-cancer effect - A glimpse to the future."

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This article was published in the following journal.

Name: Expert opinion on investigational drugs
ISSN: 1744-7658
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Clinical Trials [8045 Associated Clinical Trials listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.

A serine/threonine-specific protein kinase which is encoded by the CHEK1 gene in humans. Checkpoint kinase 1 (also known as Chk1) coordinates DNA damage response and cell cycle checkpoint response. Under these conditions, activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death, to prevent damaged cells from progressing through the cell cycle.

Substances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.

Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.

Using certified ELECTRONIC HEALTH RECORDS technology to improve quality, safety, efficiency, and reduce HEALTHCARE DISPARITIES; engage patients and families in their health care; improve care coordination; improve population and public health; while maintaining privacy and security.

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