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Long-term outcomes of varicella zoster virus infection-related myelitis in 10 immunocompetent patients.

08:00 EDT 15th August 2018 | BioPortfolio

Summary of "Long-term outcomes of varicella zoster virus infection-related myelitis in 10 immunocompetent patients."

To describe the clinical presentation and long-term disease outcomes of varicella zoster virus (VZV) infection-related myelitis (VZVM) in immunocompetent patients.

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Journal Details

This article was published in the following journal.

Name: Journal of neuroimmunology
ISSN: 1872-8421
Pages: 36-40

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Medical and Biotech [MESH] Definitions

Inflammation of brain tissue caused by infection with the varicella-zoster virus (HERPESVIRUS 3, HUMAN). This condition is associated with immunocompromised states, including the ACQUIRED IMMUNODEFICIENCY SYNDROME. Pathologically, the virus tends to induce a vasculopathy and infect oligodendrocytes and ependymal cells, leading to CEREBRAL INFARCTION, multifocal regions of demyelination, and periventricular necrosis. Manifestations of varicella encephalitis usually occur 5-7 days after onset of HERPES ZOSTER and include HEADACHE; VOMITING; lethargy; focal neurologic deficits; FEVER; and COMA. (From Joynt, Clinical Neurology, 1996, Ch 26, pp29-32; Hum Pathol 1996 Sep;27(9):927-38)

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A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus.

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