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Of ∼10.2 million people with chronic HCV infection in Europe, most are living in Eastern Europe (6.7 million) followed by Western Europe (2.3 million) and Central Europe (1.2 million). HCV transmission continues to occur - mainly through injection drug use and to a lesser degree, via nosocomial transmission - in parallel with an increasing HCV-related liver disease burden, the result of an ageing population infected during peak HCV epidemics decades prior. In 2016, the World Health Organization set targets to eliminate HCV infection as a major public health threat by 2030. Across Europe, an estimated 36% of those living with chronic HCV infection have been diagnosed and ∼5% have been treated. A major barrier to enhancing HCV treatment uptake has been restrictions set by payers, including national governments and others, in response to the initially high list prices of direct-acting antiviral (DAA) therapies. The aims of this article are to discuss DAA restrictions in Europe, why DAA restrictions are still in place, what has facilitated the removal of DAA restrictions, and what challenges remain in the region to eliminate HCV as a major public health threat by 2030.
This article was published in the following journal.
Name: Journal of hepatology
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Individuals enrolled in a school of PUBLIC HEALTH or a formal educational program in public health.
Removal of a drug from the market due to the identification of an intrinsic property of the drug that results in a serious risk to public health.
A field of study that examines the organization, financing, and delivery of public health services within communities, and the impact of these services on public health.
The ongoing, systematic collection, analysis, and interpretation of health-related data with the purpose of preventing or controlling disease or injury, or of identifying unusual events of public health importance, followed by the dissemination and use of information for public health action. (From Am J Prev Med 2011;41(6):636)
An organizational enterprise between a public sector agency, federal, state or local, and a private sector entity. Skills and assets of each sector are shared to deliver a service or facility for the benefit or use of the general public.
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