The removal of DAA restrictions in Europe - one step closer to eliminating HCV as a major public health threat.

08:00 EDT 27th June 2018 | BioPortfolio

Summary of "The removal of DAA restrictions in Europe - one step closer to eliminating HCV as a major public health threat."

Of ∼10.2 million people with chronic HCV infection in Europe, most are living in Eastern Europe (6.7 million) followed by Western Europe (2.3 million) and Central Europe (1.2 million). HCV transmission continues to occur - mainly through injection drug use and to a lesser degree, via nosocomial transmission - in parallel with an increasing HCV-related liver disease burden, the result of an ageing population infected during peak HCV epidemics decades prior. In 2016, the World Health Organization set targets to eliminate HCV infection as a major public health threat by 2030. Across Europe, an estimated 36% of those living with chronic HCV infection have been diagnosed and ∼5% have been treated. A major barrier to enhancing HCV treatment uptake has been restrictions set by payers, including national governments and others, in response to the initially high list prices of direct-acting antiviral (DAA) therapies. The aims of this article are to discuss DAA restrictions in Europe, why DAA restrictions are still in place, what has facilitated the removal of DAA restrictions, and what challenges remain in the region to eliminate HCV as a major public health threat by 2030.


Journal Details

This article was published in the following journal.

Name: Journal of hepatology
ISSN: 1600-0641


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