The dynamics of integration, viral suppression and cell-cell transmission in the development of occult hepatitis B virus infection.

08:00 EDT 30th June 2018 | BioPortfolio

Summary of "The dynamics of integration, viral suppression and cell-cell transmission in the development of occult hepatitis B virus infection."

Out of several phases of HBV infection, the least understood phase is occult hepatitis virus infection. The paucity of data due to non-availability of biological tissues and the prerequisite of ultra-sensitive assays for the detection of occult hepatitis virus infection prompted us to utilize mathematical modeling in determining mechanisms that lead to occult hepatitis virus infection and characteristics of HBV infection during occult hepatitis virus infection.


Journal Details

This article was published in the following journal.

Name: Journal of theoretical biology
ISSN: 1095-8541


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Insertion of viral DNA into host-cell DNA. This includes integration of phage DNA into bacterial DNA; (LYSOGENY); to form a PROPHAGE or integration of retroviral DNA into cellular DNA to form a PROVIRUS.

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