Production of dynamic lipid bilayers using the reversible thiol-thioester exchange reaction.

08:00 EDT 4th July 2018 | BioPortfolio

Summary of "Production of dynamic lipid bilayers using the reversible thiol-thioester exchange reaction."

Thiol lysolipids undergo thiol-thioester exchange with two phenyl thioester-functionalized tails to produce phospholipid structures that assemble into liposomes with differences in exchange rates, temperature sensitivity, permeability, and continued exchange behavior. This in situ formation reaction imparts dynamic characteristics into the membrane for downstream liposome functionalization and mimics native membrane remodeling.


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This article was published in the following journal.

Name: Chemical communications (Cambridge, England)
ISSN: 1364-548X


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