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Inter-laboratory study of the skin distribution of 4-n-butyl resorcinol in ex vivo pig and human skin.

08:00 EDT 27th June 2018 | BioPortfolio

Summary of "Inter-laboratory study of the skin distribution of 4-n-butyl resorcinol in ex vivo pig and human skin."

4-n-butyl resorcinol (4-nBR) is a highly effective tyrosinase inhibitor, and can be used in cosmetic product for depigmentation purpose. Its efficacy correlates with 4-nBR that absorbed by skin. In this study, skin distribution of 4-nBR within either human or pig skin ex vivo was studied and compared by three independent laboratories. Good agreement was observed in each compartment considering usual inter-lab variability. This study supports the use of pig skin as an alternative source of skin when the availability of human skin is a limiting factor.

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This article was published in the following journal.

Name: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
ISSN: 1873-376X
Pages: 77-79

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