Advertisement

Topics

Challenges in the analysis of novel flame retardants in indoor dust: results of the INTERFLAB 2 interlaboratory evaluation.

08:00 EDT 13th July 2018 | BioPortfolio

Summary of "Challenges in the analysis of novel flame retardants in indoor dust: results of the INTERFLAB 2 interlaboratory evaluation."

The Interlaboratory Study of Novel Flame Retardants (INTERFLAB 2) was conducted by 20 laboratories in 12 countries to test the precision and accuracy of the analysis of 24 "novel" flame retardants (NFRs). Laboratories analyzed NFRs in injection-ready test mixtures, in extracts of residential dust, and in residential dust to evaluate the influence of dust handling and extraction. For test mixtures, mean reported concentrations of PBT, PBEB, EH-TBB, TBBPA, TBDP-TAZTO, TBOEP, α-TBCO, β-DBE-DBCH, and total HBCDD differed by >25% relative to reference values. Coefficients of variation were higher in dusts/dust extracts than in test mixtures. Concentrations among laboratories ranged over 3-4 orders of magnitude for HBB, TBP-DBPE, TBP-AE, and TDCIPP in dust extracts and dusts. Most laboratories produced repeatable dust concentrations, but differences reported in the literature between laboratories of <70% could be due to analytical variability, and the attribution of such differences to other causes should be made with caution. Most variations in accuracy and precision were introduced by matrix effects, sample and/or processing rather than instrumental analysis. We recommend recovery correction to improve accuracy. There is a need to improve analytical methods and to validate methods on complex matrices such as standard reference materials for dust or spiked matrices.

Affiliation

Journal Details

This article was published in the following journal.

Name: Environmental science & technology
ISSN: 1520-5851
Pages:

Links

DeepDyve research library

PubMed Articles [28077 Associated PubMed Articles listed on BioPortfolio]

Associations between allergic symptoms and phosphate flame retardants in dust and their urinary metabolites among school children.

Phosphate flame retardants (PFRs) are ubiquitously detected in indoor environments. Despite increasing health concerns pertaining to PFR exposure, few epidemiological studies have examined PFR exposur...

Dermal contact with furniture fabrics is a significant pathway of human exposure to brominated flame retardants.

Despite extensive application in consumer products and concerns over their adverse health effects, how external exposure to brominated flame retardants (BFRs) contributes to their human body burdens i...

Comparison of rates of direct and indirect migration of phosphorus flame retardants from flame-retardant-treated polyester curtains to indoor dust.

In this study, the pathways for migration of phosphorus flame retardants (PFRs), tris(1,3-dichloroisopropyl) phosphate (TDCPP) and tricresyl phosphate (TCsP) which were detected from curtains often, f...

Presence and human exposure assessment of organophosphate flame retardants (OPEs) in indoor dust and air in Beijing, China.

In this study, levels of 14 organophosphate flame retardants (OPEs) were measured in 101 indoor dust samples collected from dormitories, residential homes, and offices in Beijing, China. In addition, ...

Polybrominated diphenyl ethers and novel brominated flame retardants in indoor dust of different microenvironments in Beijing, China.

The occurrence levels of eight polybrominated diphenyl ethers (PBDEs) and four novel brominated flame retardants (NBFRs) were determined and compared in indoor dust from different microenvironments (2...

Clinical Trials [3948 Associated Clinical Trials listed on BioPortfolio]

Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract

The purpose of this study is to serve as a pilot safety study for nasal allergen challenges.

Environment and Reproductive Health

The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as pol...

Engaging Moms on Teen Indoor Tanning Through Social Media

A sample of mothers in Tennessee are recruited to a group-randomized pretest-posttest controlled trial evaluating the effect of a social media campaign to decrease mothers' permissiveness ...

AsthmaVent - Effect of Mechanical Ventilation on Asthma Control in Children

AsthmaVent is a multi-center study, investigating the association between indoor air quality and childhood asthma. In Denmark, we spend more and more time indoors. Our houses are built ai...

Hypofractionated Focal Lesion Ablative Microboost in prostatE Cancer

The hypo-FLAME study is a multicenter phase II study (n=100) to investigate whether a focal SBRT boost to the MRI-defined macroscopic tumor volume is feasible and associated with acceptabl...

Medical and Biotech [MESH] Definitions

Materials applied to fabrics, bedding, furniture, plastics, etc. to retard their burning; many may leach out and cause allergies or other harm.

Compounds that contain two halogenated benzene rings linked via an OXYGEN atom. Many polybrominated diphenyl ethers are used as FLAME RETARDANTS.

The contamination of indoor air.

Pyrolysis of organic compounds at the temperature of a hydrogen-air flame to produce ionic intermediates which can be collected and the resulting ion current measured by gas chromatography.

Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article