Challenges in the analysis of novel flame retardants in indoor dust: results of the INTERFLAB 2 interlaboratory evaluation.

08:00 EDT 13th July 2018 | BioPortfolio

Summary of "Challenges in the analysis of novel flame retardants in indoor dust: results of the INTERFLAB 2 interlaboratory evaluation."

The Interlaboratory Study of Novel Flame Retardants (INTERFLAB 2) was conducted by 20 laboratories in 12 countries to test the precision and accuracy of the analysis of 24 "novel" flame retardants (NFRs). Laboratories analyzed NFRs in injection-ready test mixtures, in extracts of residential dust, and in residential dust to evaluate the influence of dust handling and extraction. For test mixtures, mean reported concentrations of PBT, PBEB, EH-TBB, TBBPA, TBDP-TAZTO, TBOEP, α-TBCO, β-DBE-DBCH, and total HBCDD differed by >25% relative to reference values. Coefficients of variation were higher in dusts/dust extracts than in test mixtures. Concentrations among laboratories ranged over 3-4 orders of magnitude for HBB, TBP-DBPE, TBP-AE, and TDCIPP in dust extracts and dusts. Most laboratories produced repeatable dust concentrations, but differences reported in the literature between laboratories of <70% could be due to analytical variability, and the attribution of such differences to other causes should be made with caution. Most variations in accuracy and precision were introduced by matrix effects, sample and/or processing rather than instrumental analysis. We recommend recovery correction to improve accuracy. There is a need to improve analytical methods and to validate methods on complex matrices such as standard reference materials for dust or spiked matrices.


Journal Details

This article was published in the following journal.

Name: Environmental science & technology
ISSN: 1520-5851


DeepDyve research library

PubMed Articles [28066 Associated PubMed Articles listed on BioPortfolio]

Associations between allergic symptoms and phosphate flame retardants in dust and their urinary metabolites among school children.

Phosphate flame retardants (PFRs) are ubiquitously detected in indoor environments. Despite increasing health concerns pertaining to PFR exposure, few epidemiological studies have examined PFR exposur...

Dermal contact with furniture fabrics is a significant pathway of human exposure to brominated flame retardants.

Despite extensive application in consumer products and concerns over their adverse health effects, how external exposure to brominated flame retardants (BFRs) contributes to their human body burdens i...

A review of semi-volatile organic compounds (SVOCs) in the indoor environment: occurrence in consumer products, indoor air and dust.

As many people spend a large part of their life indoors, the quality of the indoor environment is important. Data on contaminants such as flame retardants, pesticides and plasticizers are available fo...

Oral bioaccessibility of semi-volatile organic compounds (SVOCs) in settled dust: A review of measurement methods, data and influencing factors.

Many semi-volatile organic compounds (SVOCs), suspected of reprotoxic, neurotoxic or carcinogenic effects, were measured in indoor settled dust. Dust ingestion is a non-negligible pathway of exposure ...

Occupational exposure to polybrominated diphenyl ethers (PBDEs) and other flame retardant foam additives at gymnastics studios: Before, during and after the replacement of pit foam with PBDE-free foams.

Coaches spend long hours training gymnasts of all ages aided by polyurethane foam used in loose blocks, mats, and other padded equipment. Polyurethane foam can contain flame retardant additives such a...

Clinical Trials [3825 Associated Clinical Trials listed on BioPortfolio]

Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract

The purpose of this study is to serve as a pilot safety study for nasal allergen challenges.

Engaging Moms on Teen Indoor Tanning Through Social Media

A sample of mothers in Tennessee are recruited to a group-randomized pretest-posttest controlled trial evaluating the effect of a social media campaign to decrease mothers' permissiveness ...

Environment and Reproductive Health

The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as pol...

AsthmaVent - Effect of Mechanical Ventilation on Asthma Control in Children

AsthmaVent is a multi-center study, investigating the association between indoor air quality and childhood asthma. In Denmark, we spend more and more time indoors. Our houses are built ai...

SENOC-I Det Sunda Huset II - Sensitization of Occupants of Water Damaged Buildings.

The study is focussed on two main questions: 1. The importance of dampness of the building and home dust as a factor of the subjects= responses. 2. Can measures used in KL...

Medical and Biotech [MESH] Definitions

Materials applied to fabrics, bedding, furniture, plastics, etc. to retard their burning; many may leach out and cause allergies or other harm.

Compounds that contain two halogenated benzene rings linked via an OXYGEN atom. Many polybrominated diphenyl ethers are used as FLAME RETARDANTS.

The contamination of indoor air.

Pyrolysis of organic compounds at the temperature of a hydrogen-air flame to produce ionic intermediates which can be collected and the resulting ion current measured by gas chromatography.

Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.

Quick Search


DeepDyve research library

Searches Linking to this Article