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The Domino Effect in EGFR-ERK Signaling.

08:00 EDT 16th July 2018 | BioPortfolio

Summary of "The Domino Effect in EGFR-ERK Signaling."

A gradient of EGFR-ERK signaling has been classically implicated in various developmental processes. In this issue of Developmental Cell, Ogura et al. (2018) show that in the Drosophila tracheal placode, EGFR-ERK signaling propagates via a cell-by-cell relay mechanism rather than a gradient, and this sequential ERK activation controls proper placode invagination.

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Name: Developmental cell
ISSN: 1878-1551
Pages: 128-130

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