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S-protected thiolated cyclodextrins as mucoadhesive oligomers for drug delivery.

08:00 EDT 17th July 2018 | BioPortfolio

Summary of "S-protected thiolated cyclodextrins as mucoadhesive oligomers for drug delivery."

The purpose of this study was to develop a novel mucoadhesive thiolated and S-protected gamma cyclodextrin (γ-CD) with an intact ring backbone to assure a prolonged residence time at specific target sites.

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Journal Details

This article was published in the following journal.

Name: Journal of colloid and interface science
ISSN: 1095-7103
Pages: 261-268

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Medical and Biotech [MESH] Definitions

Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.

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