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Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model.

08:00 EDT 23rd July 2018 | BioPortfolio

Summary of "Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model."

In high-risk populations, allergen-specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypo-allergenic vaccine formulations. We here characterized the preventive potential of virus-like nanoparticles (VNP) expressing surface exposed or shielded allergens.

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Name: Allergy
ISSN: 1398-9995
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