In this review, we will discuss efforts and challenges in understanding and developing meaningful outcomes of critical care research, quality improvement and policy, which are patient-centered and goal concordant, rather than mortality alone. We shall discuss different aspects of what could constitute outcomes of critical illness as meaningful to the patients and other stakeholders, including families and providers.
This article was published in the following journal.
Name: Current opinion in critical care
ISSN: 1531-7072
Pages:
Plasma mitochondrial DNA and metabolomic alterations in severe critical illness.
Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is common...
To explore how nonphysicians and physicians interpret the word "treatable" in the context of critical illness.
Physical Function Trajectories in Survivors of Acute Respiratory Failure.
Survivorship from critical illness has improved, however factors mediating the functional recovery of persons experiencing a critical illness remain incompletely understood.
Patients' perceptions and ICU clinicians predictions of quality of life following critical illness.
To determine how patients perceive their quality of life (QOL) six months following critical illness and to measure clinicians' discriminative accuracy of predicting this outcome.
Pathophysiology of Critical Illness and Role of Nutrition.
Critical illness is a hypercatabolic state. It has been hypothesized that timely and adequate nutrition support may optimize the host response and thereby minimize nutritionally related complications ...
Functional Outcomes in Children Post Critical Illness
Improvements in medical care have led to decreasing mortality rates in critically ill children, which have been reported to be as low as 5%. However, surviving critical illness does not ne...
This study will identify the changes in different muscles of patients receiving Extracorporeal Membrane Oxygenation (ECMO) during critical illness and admission to Intensive Care Unit (ICU...
Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study
This study aims to determine changes in kidney function during and after critical illness, comparing conventional creatinine based methods with the gold standard to accurately establish th...
Rehabilitation Following Critical Illness
The principal research question to be answered by this study is whether an exercise based rehabilitative intervention following critical illness can generate improvements in exercise capac...
Measuring Outcomes of Activity in Intensive Care
Millions of older adults are hospitalized for a critical illness each year and although they are more likely than ever to survive this illness, they commonly face significant morbidity in ...
Critical Illness
A disease or state in which death is possible or imminent.
Catastrophic Illness
An acute or prolonged illness usually considered to be life-threatening or with the threat of serious residual disability. Treatment may be radical and is frequently costly.
Malingering
Simulation of symptoms of illness or injury with intent to deceive in order to obtain a goal, e.g., a claim of physical illness to avoid jury duty.
Critical Care Outcomes
A measure of the mortality and morbidity rates among patients who receive CRITICAL CARE and INTENSIVE CARE as determined from the date of hospital discharge or release.
Severity Of Illness Index
Levels of severity of illness within a diagnostic group which are established by various measurement criteria.