Impact of intravesical hyaluronic acid treatment on bladder inflammation in interstitial cystitis rat model.
Summary of "Impact of intravesical hyaluronic acid treatment on bladder inflammation in interstitial cystitis rat model."
To evaluate the effect of intravesical hyaluronic acid (HA) treatment on inflammatory cells and the severity of inflammation in an interstitial cystitis rat model created with hydrogen chloride (HCL) via immunohistochemical studies and myeloperoxidase activity for the first time in the literature.
Affiliation
Journal Details
This article was published in the following journal.
Name: International braz j urol : official journal of the Brazilian Society of Urology
ISSN: 1677-6119
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/30044599
- DOI: http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0713
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Medical and Biotech [MESH] Definitions
Nephritis, Interstitial
Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.
Administration, Intravesical
The instillation or other administration of drugs into the bladder, usually to treat local disease, including neoplasms.
Viscosupplementation
A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.
Cystitis, Interstitial
A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.
Idiopathic Interstitial Pneumonias
A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. They are classified by their distinct clinical-radiological-pathological features and prognosis. They include IDIOPATHIC PULMONARY FIBROSIS; CRYPTOGENIC ORGANIZING PNEUMONIA; and others.
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