Treatment for Alcohol Use Disorder: Progress in Predicting Treatment Outcome and Validating Non-Abstinent Endpoints.

08:00 EDT 26th July 2018 | BioPortfolio

Summary of "Treatment for Alcohol Use Disorder: Progress in Predicting Treatment Outcome and Validating Non-Abstinent Endpoints."

An emerging framework for multimodal assessment of addictions (Kwako et al., 2016), and expanded definitions of acceptable endpoints for alcohol treatment trials (Food and Drug Administration, 2006) are informing efforts toward personalized treatment of alcohol use disorder (AUD). A critical issue in determining for whom an intervention will work lies in the definition of clinical trial endpoints. The six articles in this virtual issue of Alcoholism: Clinical and Experimental Research illustrate recent progress in identifying predictors of alcohol treatment outcome, and pioneering work on the stability and validity of promising non-abstinent (e.g., low-risk drinking) clinical trial endpoints. As a set, the articles highlight how definitions of AUD treatment outcomes or trial end-points can influence the identification of predictors of clinical course. This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: Alcoholism, clinical and experimental research
ISSN: 1530-0277


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PubMed Articles [37142 Associated PubMed Articles listed on BioPortfolio]

Influence of comorbid drug use disorder on receipt of evidence-based treatment for alcohol use disorder among VA patients with alcohol use disorder and Hepatitis C and/or HIV.

Alcohol use is risky for patients with hepatitis C virus (HCV) and/or human immunodeficiency virus (HIV) infection, but alcohol use disorder (AUD) treatment is underutilized in these populations. Como...

Making a bridge between general hospital and specialised community-based treatment for alcohol use disorder-A pragmatic randomised controlled trial.

To investigate if more patients in the intervention group attended specialized alcohol treatment compared with a treatment-as-usual group (TAU).

Objective Continuous Monitoring of Alcohol Consumption for Three Months Among Alcohol Use Disorder Treatment Outpatients.

Transdermal alcohol sensing technology allows for objective continuous monitoring of alcohol use. The purpose of this study was to characterize alcohol consumption measured with this technology among ...

Comorbid social phobia does not predict the outcome in alcohol use disorder outpatient treatment.

Social phobia (SP) is one of the most prevalent anxiety disorders among patients entering treatment for alcohol use disorders (AUD). However, few studies have examined the association between SP and a...

Predictive value of non-consumption outcome measures in alcohol use disorder treatment.

For decades, researchers have called for the systematic inclusion of non-consumption outcomes, such as alcohol-related consequences and, temptation/craving, in addition to consumption outcomes (e.g., ...

Clinical Trials [21272 Associated Clinical Trials listed on BioPortfolio]

Talk Therapy by Phone to Promote Treatment for Alcohol Problems

A small percentage of individuals with alcohol use disorder (AUD) obtain alcohol-related care despite research showing that treatment is effective. This randomized controlled trial tests t...

Pioglitazone for the Treatment of Alcohol Use Disorder

Alcohol Use Disorder (AUD) is common among Veterans but medication treatment is used infrequently and the impact of these treatments are small to moderate at best. Pioglitazone, a medicati...

STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse

The purpose of this study is to determine if having an alcohol use disorder affects recovery from depression, and also whether recovery from depression in patients who have alcohol use dis...

Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder

The purpose of this study is to develop and test a couple-based treatment for veterans with an alcohol use disorder and post-traumatic stress disorder.

Ibudilast for the Treatment of Alcohol Use Disorder

This study is a double-blind, placebo-controlled randomized clinical trial of IBUD (50mg BID) for the treatment of Alcohol Use Disorder (AUD). Eligible participants will undergo a 12-week ...

Medical and Biotech [MESH] Definitions

Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.

An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)

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Procedures, surgery, or other treatment without consent of person or persons receiving treatment.

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