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The work proposes the development of heterogeneous bio-implants with the aim to minimize stress shielding effect and enhance bone ingrowth. Stress shielding in the implant can be minimized by reducing the overall stiffness of the implant, which is achieved here by varying the material based on stress distribution across the prosthesis. To increase overall stability of the implant by simultaneous enhancing osseointegration and reducing stress shielding, the work proposes the design of heterogeneous prosthesis with graded porosity and material having radial, axial and mixed (simultaneous radial and axial) variations. Static analysis for material variation models and consolidation analysis for graded porosity and material variation models are performed. After comparisons of results among different models, radial variation model was observed to deliver the results.
This article was published in the following journal.
Name: Journal of the mechanical behavior of biomedical materials
Development of a chromatographic step in a time and resource efficient manner remains a serious bottleneck in protein purification. Chromatographic performance typically depends on raw material attrib...
This article describes a step-by-step digital protocol for the design and fabrication, through additive manufacturing, of a splinted framework and a custom tray for the impression of a complete-arch p...
By varying the number of acetylenic linkages connecting aromatic rings, a new family of atomically thin graph-n-yne materials can be designed and synthesized. Generating immense scientific interest du...
During transcatheter aortic valve replacement with a self-expanding prosthesis, prosthesis embolization represents a rare but severe complication. Etiologies of prosthesis embolization include imprope...
Self-disgust is an emotion schema negatively affecting people's body image and is triggered by bodily imperfections and deviations from the "normal" body envelope. In this study, we explore the idea t...
The purpose of this study is to evaluate a design of prosthesis that is inexpensive and able to fit a multitude of individuals. This may offer an off the shelf item for those that cannot a...
The aim of this observational study is: producing complete dental prosthesis with the aid of CAD-CAM (Computer aided design & manufacturing) - 3D printing (Stereolithography) technology - ...
Both HA coated and certain uncoated stems have good results in general. On the cup side the results are more variable, either with or without HA. HA may delaminate from the prosthesis, da...
Often prosthesis users abandon their devices due to difficulties in prosthesis control and lack of motivation to train. To properly control a prosthesis, amputation patients must learn how...
Musculoskeletal disorders are an heterogeneous group of diseases that represent one of the major causes of disability. Considering the importance of studying these pathologies, it is neces...
The plan and delineation of dental prostheses in general or a specific dental prosthesis. It does not include DENTURE DESIGN. The framework usually consists of metal.
The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.
The plan and delineation of prostheses in general or a specific prosthesis.
An approach, process, or methodology which emphasizes credible evidence and the best available scientific knowledge, judiciously integrated to achieve the best possible outcomes in structural design. For example, the design of a new OUTPATIENT CLINIC might incorporate a review of published research on outpatient clinic design, decisions on similar past projects, along with interviews with staff and consumers.
The retention of a dental prosthesis in place by design, device, or adhesion.
Arthroplasty is a surgical procedure to restore the integrity and function of a joint. A joint can be restored by resurfacing the bones. An artificial joint (called a prosthesis) may also be used. Various types of arthritis may affect the joints. Osteo...
Adhd Anorexia Depression Dyslexia Mental Health Psychiatry Schizophrenia Stress Mental health, although not being as obvious as physical health, is very important, causing great unhappiness to those affected, causing add...
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...