Endothelial function and dysfunction: impact of metformin.

08:00 EDT 26th July 2018 | BioPortfolio

Summary of "Endothelial function and dysfunction: impact of metformin."

Cardiovascular and metabolic diseases remain the leading cause of morbidity and mortality worldwide. Endothelial dysfunction is a key player in the initiation and progression of cardiovascular and metabolic diseases. Current evidence suggests that the anti-diabetic drug metformin improves insulin resistance and protects against endothelial dysfunction in the vasculature. Hereby, we provide a timely review on the protective effects and molecular mechanisms of metformin in preventing endothelial dysfunction and cardiovascular and metabolic diseases.


Journal Details

This article was published in the following journal.

Name: Pharmacology & therapeutics
ISSN: 1879-016X


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