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Caenorhabditis elegans as a model organism for aging: relevance, limitations and future.

07:03 LMT 1st January 0000 | BioPortfolio

Summary of "Caenorhabditis elegans as a model organism for aging: relevance, limitations and future."

Aging is a physiological and complex process associated with increasing age of living organisms. Simple model organisms have brought significant advances in our understanding of the aging process. Caenorhabditis elegans, a nematode originally used to establish the genetic and molecular basis of development, has become one of the leading model organisms for research on aging. This invertebrate has allowed identifying a connection between cellular signaling pathways and longevity. Although C. elegans is not suitable for analysis of the complete process of human aging, it remains a model of choice to analyze specific aging mechanisms and phenotypes.

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This article was published in the following journal.

Name: Medecine sciences : M/S
ISSN: 1958-5381
Pages: 571-579

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A genus of small free-living nematodes. Two species, CAENORHABDITIS ELEGANS and C. briggsae are much used in studies of genetics, development, aging, muscle chemistry, and neuroanatomy.

Proteins from the nematode species CAENORHABDITIS ELEGANS. The proteins from this species are the subject of scientific interest in the area of multicellular organism MORPHOGENESIS.

A species of nematode that is widely used in biological, biochemical, and genetic studies.

A family of structurally related proteins that were originally discovered for their role in cell-cycle regulation in CAENORHABDITIS ELEGANS. They play important roles in regulation of the CELL CYCLE and as components of UBIQUITIN-PROTEIN LIGASES.

A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.

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