Advertisement

Topics

Survey of screening methods, rates and policies for the detection of carbapenemase producing Enterobacteriaceae in English hospitals.

08:00 EDT 6th August 2018 | BioPortfolio

Summary of "Survey of screening methods, rates and policies for the detection of carbapenemase producing Enterobacteriaceae in English hospitals."

Multi-drug resistant Gram negative bacteria are of major clinical concern. The increasing prevalence of carbapenemase-producing Enterobacteriaceae (CPE), resistant to all beta-lactams including carbapenems, and able to colonise the large intestine represent a key threat. Rapid, accurate detection of intestinal CPE colonisation is critical to minimise transmission, and hence reduce costly, difficult to treat CPE infections. There is currently no 'gold standard' CPE detection method. Following a survey of diagnostic laboratories in England, we report considerable heterogeneity in diagnostic CPE testing methods and procedures.

Affiliation

Journal Details

This article was published in the following journal.

Name: The Journal of hospital infection
ISSN: 1532-2939
Pages:

Links

DeepDyve research library

PubMed Articles [24070 Associated PubMed Articles listed on BioPortfolio]

Point prevalence survey of carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) in adult inpatients in a University teaching hospital in the United Kingdom.

Infections with carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) are associated with increased morbidity and mortality, but the carriage rates of CRE and VRE...

Rapid detection of carbapenemase-producing Acinetobacter baumannii and carbapenem-resistant Enterobacteriaceae using a bioluminescence-based phenotypic method.

Accurate detection of carbapenem-resistant Enterobacteriaceae (CRE) and carbapenemase-producing carbapenem-resistant Acinetobacter spp. (CP-CRA) constitutes a major challenge in laboratory diagnostics...

MALDI-TOF for the rapid detection of carbapenemase-producing Enterobacteriaceae: comparison of the commercialized MBT STAR®-Carba IVD Kit with two in-house MALDI-TOF techniques and the RAPIDEC® CARBA NP.

There is an urgent need for accurate and fast diagnostic tests to identify carbapenemase-producing bacteria. Here, we have evaluated three MALDI-TOF-based techniques to detect carbapenemase-producing ...

Evaluating the benefit of serial screening cultures to detect carbapenemase-producing Enterobacteriaceae (CPE) following hospital admission.

Carbapenem-producing Enterobacteriaceae (CPE) are on the rise worldwide. National guidelines for the prevention and control of CPE recommend screening for the detection of asymptomatic carriers on adm...

Comparison of Carba NP-Direct, Carbapenem Inactivation Method, and β-CARBA Tests for Detection of Carbapenemase Production in Enterobacteriaceae.

Rapid and accurate detection of carbapenemase-producing isolates are extremely important for management of antimicrobial therapy and the implementation of infection control measures. We evaluated the ...

Clinical Trials [8394 Associated Clinical Trials listed on BioPortfolio]

Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacteriaceae in Solid Organ Transplantation: an Observational Multinational Study.

Main objective: to observationally assess the efficacy and safety of different antimicrobials in BSI due to ESBL or carbapenemase-producing Enterobacteriaceae in SOT. Secondary objectives...

Colonoscopic Adenoma and Advanced Neoplasia Detection Rates According to Age

Current recommendations for colonoscopy screening programs usually involve patients older than 50 years of age. However, little is known about polyp or adenoma detection rates under 50. We...

Detection of Colorectal Adenomas in Côte-d'Or

Previous studies have shown geographic disparities in the detection of colorectal adenomas in Côte-d'Or, with an impact of the distance from the general practitioner and an ecological dep...

Survey of ColoRectal Cancer Education and Environment Needs

Despite strong evidence for the effectiveness and cost-effectiveness of a variety of colorectal cancer (CRC) screening methods for reducing CRC mortality, current CRC screening rates fall ...

Survey of Prostate Cancer in Accra, Ghana

This study, conducted at Korle-Bu Hospital in Accra, Ghana, will help elucidate the roles of lifestyle and genetic factors in prostate cancer risk. There is a strong variation in risk of p...

Medical and Biotech [MESH] Definitions

Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.

The identification of selected parameters in newborn infants by various tests, examinations, or other procedures. Screening may be performed by clinical or laboratory measures. A screening test is designed to sort out healthy neonates (INFANT, NEWBORN) from those not well, but the screening test is not intended as a diagnostic device, rather instead as epidemiologic.

The simultaneous use of multiple laboratory procedures for the detection of various diseases. These are usually performed on groups of people.

A class of natural contraceptive methods in which SEXUAL ABSTINENCE is practiced a few days before and after the estimated day of ovulation, during the fertile phase. Methods for determining the fertile period or OVULATION DETECTION are based on various physiological indicators, such as circulating hormones, changes in cervical mucus (CERVIX MUCUS), and the basal body temperature.

Methods used to measure the relative activity of a specific enzyme or its concentration in solution. Typically an enzyme substrate is added to a buffer solution containing enzyme and the rate of conversion of substrate to product is measured under controlled conditions. Many classical enzymatic assay methods involve the use of synthetic colorimetric substrates and measuring the reaction rates using a spectrophotometer.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topic

Drug Discovery
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...


Searches Linking to this Article