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Adrenomedullin reduces secondary injury and improves outcome in rats with fluid percussion brain injury.

08:00 EDT 7th August 2018 | BioPortfolio

Summary of "Adrenomedullin reduces secondary injury and improves outcome in rats with fluid percussion brain injury."

Traumatic brain injury (TBI) is a devastating neurological injury, and remains as a major cause of death in the world. Secondary injury after TBI is associated with long-term disability in patients with TBI. The present study evaluated adrenomedullin (AM) on secondary injury and neurological functional outcome in rats after TBI.

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This article was published in the following journal.

Name: World neurosurgery
ISSN: 1878-8769
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A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.

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