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The United States (US) Food and Drug Administration (FDA) is taking unprecedented steps to regulate tobacco products in order to improve public health. The FDA recently announced its intention to set product standards to reduce the nicotine content in cigarettes available in the US to a minimally- or non-addictive level through an advance notice of proposed rulemaking (ANPRM) (Gottlieb and Zeller, 2017). Because of the strong connection of cigarette smoking to alcohol drinking, there is compelling reason for alcohol-focused researchers to consider how future mandated market-wide reductions of nicotine levels in cigarettes would have downstream impact on drinking behavior. This article is protected by copyright. All rights reserved.
This article was published in the following journal.
Name: Alcoholism, clinical and experimental research
Simultaneous alcohol and nicotine consumption occurs in the majority of individuals with alcohol use disorder (AUD) and nicotine dependence. Varenicline (Var) is used to assist in the cessation of nic...
Electronic nicotine delivery system (ENDs) use has increased in prevalence over the last decade, which has led to questions about their public health impact. In this article, we explore the emergent r...
Alcohol is the most commonly used drug in the United States and alcohol abuse can lead to alcohol use disorder. Alcohol use disorder is a persistent condition and relapse rates following successful re...
Smoking is the leading cause of preventable death in the United States. An FDA-mandated reduction in the nicotine content of cigarettes might reduce the health burden of tobacco by reducin...
The purpose of this study is to investigate the impact of different nicotine levels in cigarettes with individuals who have ADHD.
This study examines the potential effect of reducing nicotine content or menthol or both in women of reproductive age, a vulnerable population identified by the FDA in need of further rese...
This is a 2-year study involving the progressive reduction in the nicotine content of cigarettes. The investigators believe that at the end of the study smokers of cigarettes with progress...
The overall goal of this study is to determine if switching to very low nicotine content cigarettes changes the function of brain circuitry involved in incentive salience and executive con...
Mass of alcohol per unit of BLOOD volume.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
A sugar alcohol formed by the reduction of ribose.
Component of the NATIONAL INSTITUTES OF HEALTH. It conducts research focused on improving the treatment and prevention of alcoholism and alcohol-related problems to reduce the health, social, and economic consequences of this disease. NIAAA, NIMH, and NIDA were created as coequal institutes within the Alcohol, Drug Abuse and Mental Health Administration in 1974. It was established within the NATIONAL INSTITUTES OF HEALTH in 1992.
System through which research and other scholarly writings are created, evaluated for quality, disseminated to the scholarly community, and preserved for future use. It includes both formal means of communication, such as publication in peer-reviewed journals, and informal channels, such as electronic listservs. (from Association of College & Research Libraries, “Principles and Strategies for the Reform of Scholarly Communication 1,” 2003)
In order to become availible to pateints, drugs need to undergo a number of phases of clinical trials to test their efficacy and safty and to then be authorised by the drug approval organistion in each respective country. This is the FDA in the USA and N...
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