Prostatic capsular incision during radical prostatectomy has important oncological implications. A systematic review and meta-analysis.

08:00 EDT 16th August 2018 | BioPortfolio

Summary of "Prostatic capsular incision during radical prostatectomy has important oncological implications. A systematic review and meta-analysis."

Capsular Incision (CapI) is an iatrogenic breach of the prostatic capsule during radical prostatectomy that can cause positive surgical margins (PSM) in organ-confined (pT2) prostate cancer (PCa), or the retention of benign prostatic tissue. We systematically interrogated the literature in order to clarify the definition of CapI, and the implications of this event for rates of PSM and biochemical recurrence (BCR).


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This article was published in the following journal.

Name: BJU international
ISSN: 1464-410X


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Medical and Biotech [MESH] Definitions

A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.

Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).

The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.

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Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.

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