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This study compared the antibacterial effect of 2% clindamycin and 2% and 100% concentration of triple antibiotic paste (TAP) on an Enterococcus faecalis biofilm. Dentinal tubules of 100 root specimens were infected and randomly assigned to five groups. A total of 1000 mg mL of TAP, 20 mg mL of TAP and clindamycin, calcium hydroxide or methylcellulose (control) were placed in the root canal for 1 week. After treatment, dentine shavings were collected from 200 and 400 μm dentine depth and the number of colony-forming units (CFU) per mg was determined. Reduction in viable bacteria in first three groups was significantly better than calcium hydroxide and control groups. However, the antimicrobial effectiveness among these three groups was not significantly different from each other. There was no significant difference between data at 200 and 400 μm in all groups except the Ca(OH) group. The antibiofilm effect of clindamycin was comparable with TAP, so it may be used instead of TAP.
This article was published in the following journal.
Name: Australian endodontic journal : the journal of the Australian Society of Endodontology Inc
Long term success in endodontic therapy is attributed to removal and debridement of intracanal microorganisms. The aim of this study was to compare the antimicrobial effects calcium hydroxide (Ca(OH))...
The aim is to test the antimicrobial activity of , (neem), and (curcumin) as a root canal irrigant, against and using agar diffusion test. Sodium hypochlorite (NaOCl) served as a standard control ...
To investigate the anti-biofilm efficacy of root canal irrigants in canal spaces, isthmi and dentinal tubules of root canals ex vivo.
The root and canal anatomy of the mandibular first molar is highly complicated. A mandibular first molar with a C-shaped root canal system is rare. This article describes two different cases of this s...
The aim of this in vitro study was to evaluate the preventive efficacy of three dentin tubule occlusion methods against discoloration caused by triple-antibiotic paste (TAP). Sixty extracted human inc...
The purpose of the investigators study is to characterize the composition of the hard and soft tissues present in root canals of teeth previously diagnosed with necrotic pulps and incomple...
Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.
This Study Was Made to Evaluate the Antibacterial Effect of Different Antibacterial Combinations on Revascularization Process in Permanent Anterior Immature Teeth. Immature Necrotic Perman...
The purpose of this study is to determine whether the use of triple antibiotic paste as intracanal medication with and without an anti-inflammatory drug, compared to a calcium hydroxide wi...
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1. Cl...
This is a controlled, randomized, double-blind clinical study (researcher and research participant does not know which group they belong to), with the objective of evaluating clinical and ...
Materials placed inside a root canal for the purpose of obturating or sealing it. The materials may be gutta-percha, silver cones, paste mixtures, or other substances. (Dorland, 28th ed, p631 & Boucher's Clinical Dental Terminology, 4th ed, p187)
Programs and guidelines for selecting optimal ANTI-INFECTIVE AGENTS regimens in an effort to maintain antibiotic efficacy, reduce CROSS INFECTION related to ANTIBIOTIC RESISTANCE while managing satisfactory clinical and economic outcomes.
Preparatory activities in ROOT CANAL THERAPY by partial or complete extirpation of diseased pulp, cleaning and sterilization of the empty canal, enlarging and shaping the canal to receive the sealing material. The cavity may be prepared by mechanical, sonic, chemical, or other means. (From Dorland, 28th ed, p1700)
Phase of endodontic treatment in which a root canal system that has been cleaned is filled through use of special materials and techniques in order to prevent reinfection.
Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.
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Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...