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Bazedoxifene-induced vasodilation and inhibition of vasoconstriction is significantly greater than estradiol.

08:00 EDT 20th August 2018 | BioPortfolio

Summary of "Bazedoxifene-induced vasodilation and inhibition of vasoconstriction is significantly greater than estradiol."

A new strategy for menopausal hormone therapy replaces medroxyprogesterone with the selective estrogen receptor modulator bazedoxifene. While the agonist or antagonist activity of bazedoxifene has been examined in other tissues, the current study explored the impact of bazedoxifene on resistance artery reactivity. We hypothesized that bazedoxifene may induce greater vasoprotective effects than estradiol due to enhanced activation of the G-protein-coupled estrogen receptor.

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Name: Menopause (New York, N.Y.)
ISSN: 1530-0374
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