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Impact of a higher fecal immunochemistry test cut-off on pathology detected in subsequent rounds of a colorectal screening program.

08:00 EDT 21st August 2018 | BioPortfolio

Summary of "Impact of a higher fecal immunochemistry test cut-off on pathology detected in subsequent rounds of a colorectal screening program."

Fecal immunochemical test (FIT)-based colorectal cancer (CRC) screening is superior to the traditional binary fecal occult blood (FOB) test. Its quantitative nature allows the investigator to choose a positivity threshold, to match cost and endoscopic capacity. The optimal threshold is still debated. BowelScreen, the Irish national colorectal cancer screening program, has a cut-off of 45μ Hb/g feces and in this study, we investigated the impact of a this threshold on pathology detected in round 2 in individuals who had a negative round 1 FIT (FIT).

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This article was published in the following journal.

Name: Gastrointestinal endoscopy
ISSN: 1097-6779
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