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The chiral signatures and environmental behaviors of chiral polychlorinated biphenyls (PCBs) have been extensively studied. However, information regarding chiral PCBs in invertebrates, especially earthworms, is limited. This study aimed to investigate the stereoselective bioaccumulation, elimination, and biotransformation of chiral PCBs 95 and 149 in an earthworm-soil system. Preferential enrichment of (+)-atropisomers and elimination of (-)-atropisomers were observed, for both PCBs 95 and 149, during the uptake and elimination phases, respectively, leading to higher enantiomer fractions (EFs). A significant linear correlation between the total concentrations of chiral PCBs and EF values was found in earthworms. The EF values increased with the increase in exposure time and further increased during the elimination phase, indicating the biotransformation of chiral PCBs. Hydroxylated metabolites of PCB 95 were found in earthworms for the first time, thus verifying the ability of earthworms to metabolize chiral PCBs. However, no methylsulfonyl metabolites were observed for PCBs 95 and 149. These findings might be helpful for understanding the biological processes of chiral PCBs in species at lower trophic levels.
This article was published in the following journal.
N-ethyl perfluorooctane sulfonamide (N-EtFOSA) is commonly known as the active ingredient of sulfluramid. It can be degraded to perfluorooctane sulfonic acid (PFOS) in biota and environment. Earthworm...
Managing municipal green waste is a challenge to municipalities, partly because of the slow rate of decomposition of green waste during composting due to its high lignin and cellulose contents. Hence,...
In recent years, increasing efforts have focused on production of organic-inorganic compound fertilizers using ammonium sulfite pulping waste liquor. However, their ecological effects on soil have not...
Soil environment contaminated by Escherichia coli O157:H7 which come from the waste of infected animals. Earthworms can live in the pathogens-polluted soil by their innate immunity. How the proteins o...
Chirality is a critical topic in the medicinal and agrochemical fields. One quarter of all agrochemicals was chiral in 1996, and this proportion has increased remarkably with the introduction of new c...
Primary objectives: 1. To comprehensively characterize steady state stereoselective pharmacokinetics of bupropion and its primary and secondary metabolites in healthy volunteers ...
The purpose of this interventional study is to test and compare the effectiveness of two elimination diets—the 1-food elimination diet (1FED, milk only) and the 4-food elimination diet (...
In line with the global and regional efforts towards malaria elimination, a five year program was established to assist the NMCP in adopting targeted evidence-based elimination plans throu...
The purpose of this interventional study is to test and compare the effectiveness of two elimination diets—the 1-food elimination diet (1FED, milk only) and the 6-food elimination diet (...
The use of LGG will be associated with elimination of VRE colonization. The primary comparison will be VRE elimination rates among those patients that receive LGG compared to those that r...
Polymers of N-SUBSTITUTED GLYCINES containing chiral centers at the a-position of their side chains. These oligomers lack HYDROGEN BONDING donors, preventing formation of the usual intrachain hydrogen bonds but can form helices driven by the steric influence of chiral side chains.
A class of annelid worms with few setae per segment. It includes the earthworms such as Lumbricus and Eisenia.
A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN.
Enzymes that catalyze the epimerization of chiral centers within carbohydrates or their derivatives. EC 5.1.3.
A factor associated with the well-being of living organisms that is used as a measure of environmental change and or influence. For example, aldehyde dehydrogenase expression in earthworm tissue is used as an indication of heavy metal pollution in soils. Distinguish from BIOMARKERS.
Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions of such substances to treat disease. Some biological therapies for cancer use vaccines or bacteria to stimulate the body&rs...