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Haplotype matching in large cohorts using the Li and Stephens model.

08:00 EDT 25th August 2018 | BioPortfolio

Summary of "Haplotype matching in large cohorts using the Li and Stephens model."

The Li and Stephens model, which approximates the coalescent describing the pattern of variation in a population, underpins a range of key tools and results in genetics. Although highly efficient compared to the coalescent, standard implementations of this model still cannot deal with the very large reference cohorts that are starting to become available, and practical implementations use heuristics to achieve reasonable runtimes.

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This article was published in the following journal.

Name: Bioinformatics (Oxford, England)
ISSN: 1367-4811
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