Advertisement

Topics

Comment on ' Role of platelet-rich fibrin on intestinal anastomosis wound healing in a rat'.

08:00 EDT 3rd September 2018 | BioPortfolio

Summary of "Comment on ' Role of platelet-rich fibrin on intestinal anastomosis wound healing in a rat'."

Platelet-rich fibrin (PRF) is indeed a promising treatment modality for healing promotion and acceleration. Are there, however, any disadvantages or contraindications regarding its safety when applied on intestinal anastomosis after tumor excision? The regenerative effect of PRF in a malignant microenvironment, deserves further experimental investigation and large-scale prospective randomized clinical trials, that could provide an indication of the extent to which the tumor cell instructs its microenvironment versus the microenvironment instructing the tumor.

Affiliation

Journal Details

This article was published in the following journal.

Name: Biomedical materials (Bristol, England)
ISSN: 1748-605X
Pages:

Links

DeepDyve research library

PubMed Articles [14443 Associated PubMed Articles listed on BioPortfolio]

Reply to Comment on ' Role of platelet-rich fibrin on intestinal anastomosis wound healing in a rat'.

.

Effects of Platelet Concentrates Used in Alveolar Ridge Preservation: A Systematic Review.

The purpose of the review was to investigate the efficacy of platelet concentrates (containing pure platelet-rich plasma, leukocyte- and platelet-rich plasma, pure platelet-rich fibrin, and leukocyte-...

Comparison of platelet rich plasma versus fibrin glue on colonic anastomoses in rats.

To compare platelet rich plasma (PRP) and fibrin glue about the effect of anastomotic healing.

Bone regeneration around immediate placed implant of molar teeth with autologous platelet-rich fibrin: Two case reports.

There are some challenges concerning immediate implant placement in molar region. Platelet-rich fibrin (PRF), a second generation platelet concentrate, is an autologous fibrin matrix and contains plat...

Comparison of the Regenerative Effects of Platelet-Rich Fibrin and Plasma Rich in Growth Factors on Injured Peripheral Nerve: An Experimental Study.

The aim of this study was to investigate the effects of platelet-rich fibrin (PRF) and plasma rich in growth factors (PRGF) on peripheral nerve injury in the early period of healing.

Clinical Trials [5482 Associated Clinical Trials listed on BioPortfolio]

Evaluation of the Mechanism of Action of Platelet Rich Fibrin Matrix (PRFM) in Producing Skin Volume Augmentation

Autologous platelet rich fibrin matrix will release growth factors which could increase the production of dermal proteins or affect the vascularity and status of neighboring tissues. This ...

Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects

This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the...

Effects of Platelet Rich Fibrin (PRF) in Treatment of Non-healing Sternum Wound After Open-heart Surgery

Sternal wound and there complication such as infection, Bruising and scar formation are known as major complication cardiac surgery with a high mortality rate up to 50%. Several approaches...

Treatment of Periodontal Intrabony Defects Using Autologous Platelet Rich Fibrin vs Titanium Platelet Rich Fibrin

Background: To compare the effectiveness of open flap debridement (OFD) alone and OFD along with either Autologous Platelet Rich Fibrin (PRF) or Titanium Platelet Rich Fibrin (TPRF) in the...

Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession

This research will be conducted in an attempt to achieve complete root coverage with physiologic probing depth and a harmonious view with the adjacent tissues using Platelet rich fibrin in...

Medical and Biotech [MESH] Definitions

A fibrin matrix derived from platelet-rich plasma that contains high concentration of BLOOD PLATELETS; LEUKOCYTES; CYTOKINES; and GROWTH FACTORS. It is used in a variety of clinical and TISSUE ENGINEERING applications.

A preparation consisting of PLATELETS concentrated in a limited volume of PLASMA. This is used in various surgical tissue regeneration procedures where the GROWTH FACTORS in the platelets enhance wound healing and regeneration.

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

Retraction of a clot resulting from contraction of PLATELET pseudopods attached to FIBRIN strands. The retraction is dependent on the contractile protein thrombosthenin. Clot retraction is used as a measure of platelet function.

Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...

Complementary and Alternative Medicine
Alternative medicine are whole medical systems that did not fit with conventional medicine as they have completely different philosophies and ideas on the causes of disease, methods of diagnosis and approaches to treatment. Although often overlapping, co...

Clinical Approvals
Clinical trials are a set of procedures in medical research conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and efficacy data to be collected for health interventions (e.g...


Searches Linking to this Article