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The preschool period is a time of significant physical and behavioral growth, including the improvement of gross and fine motor skills. Although motor development has been comprehensively mapped from infancy to adulthood, the neural correlates associated with motor advancements during early childhood remain unclear. The current study used diffusion tensor imaging (DTI) to delineate key motor pathways and characterize their relationships with motor performance in 80 typically developing preschool children, aged 3-6 years. The Movement Assessment Battery for Children-2nd edition (MABC-II) was used to assess motor functioning. Partial correlations between DTI parameters and motor performance, controlling for sex and age, revealed a positive correlation between motor performance and fractional anisotropy of corpus callosum motor fibers, as well as negative correlations of motor performance with mean and radial diffusivity. These results appear to be driving by females, as correlations were significant in girls but not boys when analyzed separately. Mean corticospinal tract (CST) diffusion parameters were not significantly related to motor performance, but relationships were observed at regionally specific locations along the bilateral CST. These findings suggest preschool-aged children with better motor performance show more mature white matter patterns within motor pathways, and that the structural variation in these pathways may partially account for the natural variability in motor performance.
This article was published in the following journal.
Already in preschool, very preterm (VP) children perform worse than term born-children on preschool mathematical skills tests. Strong associations have been found between preschool mathematical skills...
Psychomotor retardation and reduced daily activities are core features of the depressive syndrome including bipolar disorder (BD). It was the aim of this study to investigate white matter microstructu...
White matter microstructure can be measured with diffusion tensor imaging (DTI). While increasing age is a predictor of white matter (WM) microstructure changes, roles of other possible modifiers, suc...
Executive control is a higher-level cognitive function that involves a range of different processes that are involved in the planning, coordination, execution, and inhibition of responses. Many of the...
The aim of this study was to determine whether carpal tunnel syndrome (CTS) patients manifest changes in early-stage motor function and to investigate the utility of a gyrosensor for quantitative eval...
The purpose of this study is to assess the neurological development at three years of age of children born after prenatal diagnosis of "isolated" agenesis of the corpus callosum.
Agenesis of the corpus callosum (ACC) is one of the most frequent cerebral malformations and is now diagnosed prenatally in most cases. Prenatal counseling is then challenging because of u...
Patients with COPD have lower capability of activating their muscles. At the cortical level, force production is not only controlled by contralateral primary motor cortex but also by ipsil...
To investigate the relationship between the integrity of the white matter, including the corticospinal tracts and the corpus callosum, with the recovery of lower extremity function in pati...
Corpus callosum malformation (CCM) is the most frequently detected cerebral defect diagnosed in the prenatal setting. The most common CCM is corpus callosum agenesis (CCA) which is found i...
Birth defect that results in a partial or complete absence of the CORPUS CALLOSUM. It may be isolated or a part of a syndrome (e.g., AICARDI'S SYNDROME; ACROCALLOSAL SYNDROME; ANDERMANN SYNDROME; and HOLOPROSENCEPHALY). Clinical manifestations include neuromotor skill impairment and INTELLECTUAL DISABILITY of variable severity.
Set of nerve fibers that cross the midline of the TELENCEPHALON. They include the ANTERIOR COMMISSURE; the CORPUS CALLOSUM; and the HIPPOCAMPAL COMMISSURE of the fornix.
A rare genetic disorder characterized by partial or complete absence of the CORPUS CALLOSUM, resulting in infantile spasms, MENTAL RETARDATION, and lesions of the RETINA or OPTIC NERVE.
Complete severing of the CORPUS CALLOSUM. In humans it is usually performed to treat medically intractable, multifocal EPILEPSY. EXPERIMENTAL ANIMAL MODELS of split brain preparations are used in research.
Mild or moderate loss of motor function accompanied by spasticity in the lower extremities. This condition is a manifestation of CENTRAL NERVOUS SYSTEM DISEASES that cause injury to the motor cortex or descending motor pathways.
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...