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Familial aggregation of metabolic traits in NAFLD is well documented. However, relevance of these traits in alcoholic cirrhosis is not well studied. We aimed to explore the association of family history of metabolic traits with age at diagnosis, severity and complications of alcoholic cirrhosis.
This article was published in the following journal.
Name: Liver international : official journal of the International Association for the Study of the Liver
Gestational diabetes (GDM) is recognized as a major risk factor for the development of type 2 diabetes (T2DM) later in life. Risk allele carriers at TCF7L2 rs7903146 have increased susceptibility for ...
Systemic inflammation, endothelial dysfunction and deficient vascularization of either uterus or myocardium are mechanistic hallmarks of early-onset preeclampsia and heart failure with preserved eject...
Early life adversity is associated with both metabolic impairment and depression in adulthood, as well as with poorer responses to antidepressant medications. It is not yet known whether individual di...
Girls remain an understudied group when examining delinquency. Callous-unemotional traits are chief among personality traits that relate to delinquency. Some suggest, however, that girls who evince ca...
Whereas familial forms of complex disorders/differences of sex development have been widely reported, data regarding isolated hypospadias are sparse and a family history is thought to be less frequent...
We are doing this study to learn more about the early history of universal screening for metabolic disorders such as PKU and galactosemia. In particular, we are interested in learning fro...
The purpose of this study will be to demonstrate the safety, tolerability, and efficacy of arimoclomol in subjects with SOD1 positive familial ALS. This type of ALS is HEREDITARY (runs in ...
Development of a new MS-based biomarker for the early and sensitive diagnosis of Transthyretin-Related Familial Amyloidotic Polyneuropathy from plasma. Testing for clinical robustness, spe...
RATIONALE: Screening for early pancreatic neoplasia may improve the ability to detect cancer in people who have a genetic risk for pancreatic cancer. PURPOSE: Phase I trial to study the e...
Homozygous Familial Hypercholesterolemia (HoFH) is a rare genetic metabolic disorder characterized by absent or severely reduced capacity to catabolize circulating LDL particles by the hep...
Morphological or behavioral traits influenced by various living conditions that a population encounters especially as it pertains to REPRODUCTION and survival of the population (see POPULATION DYNAMICS) such as age at first reproductive event, number and size of offspring, and lifespan.
The period of history from 1451 through 1600 of the common era.
Brain disorders resulting from inborn metabolic errors, primarily from enzymatic defects which lead to substrate accumulation, product reduction, or increase in toxic metabolites through alternate pathways. The majority of these conditions are familial, however spontaneous mutation may also occur in utero.
The stealing of corpses after burial, especially for medical dissection. In the late 18th and early 19th centuries, in the absence of laws governing the acquisition of dissecting material for the study of anatomy, the needs of anatomy classes were met by surreptitious methods: body-snatching and grave robbing. The infamous practice of "burking", murder to procure bodies for dissection, was given the name of a rascal named W. Burke, hanged in Edinburgh in 1829. (Random House Unabridged Dictionary, 2d ed; from Garrison, An Introduction to the History of Medicine, 4th ed, p447; from Castiglioni, A History of Medicine, 2d ed, p676)
The study of literature in its widest sense, including grammar, etymology, criticism, literary history, language history, linguistic history, systems of writing, and anything else that is relevant to literature or language viewed as literature. Philology as a discipline has both philosophical and scientific overtones.
Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyles change, with alcoholism and cancer becoming more promi...