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The authors consider the importance of a careful, balanced review of therapeutic options with patients and the current understanding of the therapeutic ratio of whole-brain radiotherapy in patient populations with widespread intracranial disease. The goal of reviewing these options is to provide an unbiased discussion of the potential benefits and risks of whole-brain radiotherapy, particularly with regard to cognitive outcomes.
This article was published in the following journal.
To examine the outcomes of concurrent versus sequential whole-brain radiotherapy (WBRT) and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) in nonsmall cell lung cancer (NSCLC) p...
Until 50% of patients with renal cancer or melanoma, develop brain metastases during the course of their disease. Stereotactic radiotherapy has become a standard of care for patients with a limited nu...
We reviewed clinical characteristics, treatment outcomes of patients treated for Non-Small Cell Lung Cancer with brain metastases with whole brain radiotherapy plus conventional boost at a single inst...
Fear of progression (FoP) is frequent in patients with cancer and of high clinical relevance. Despite the often devastating prognosis of brain cancer, FoP has not yet been assessed in neurooncological...
Proton beam radiotherapy (PBT) has been increasingly utilized to treat pediatric brain tumors, however, limited information exists regarding radiation induced cerebral microbleeds (CMBs) among these p...
The purpose of this study is to use brain imaging technology to investigate brain changes in people exposed to predictable versus unpredictable unpleasant stimuli. Unpleasant events that c...
The proposed research aims to isolate brain-based information-processing mechanisms implicated in perturbed fear learning and extinction characteristic of pediatric anxiety. The study wil...
Since the 2000s, the experiences of children and especially their fear during a consultation, a treatment or examination is food for thought in our establishment. There is no tool validate...
Anxiety disorders are among the most prevalent, costly, and disabling mental illnesses. One central, yet largely understudied, abnormality in anxiety disorders is the heightened tendency t...
The purpose of this study is to find out more about how the brain stores emotional learning in obsessive-compulsive disorder (OCD). In particular, we would like to understand how human bei...
Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.
Anxiety disorder characterized by the persistent and irrational fear, anxiety, or avoidance of social or performance situations.
Intense or irrational dislike or fear of anything that is strange or foreign, particularly of people who are strangers or foreigners. It is an attitudinal orientation of hostility against non-natives in a given population that includes attitudes, prejudices and behavior that reject, exclude or vilify persons, based on the perception that they are outsiders or foreigners to the community, society or national identity.
Mistakes committed in the preparations for radiotherapy, including errors in positioning of patients, alignment radiation beams, or calculation of radiation doses.
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.