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Antiepileptic Drugs are associated with Central Hypothyroidism.

08:00 EDT 8th September 2018 | BioPortfolio

Summary of "Antiepileptic Drugs are associated with Central Hypothyroidism."

Studies in children have shown an increased frequency of central hypothyroidism (CH) with long term use of antiepileptic drugs (AEDs). The aim of this study was to search for CH in adults treated with AEDs and find if the type of AEDs used matters.

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Journal Details

This article was published in the following journal.

Name: Acta neurologica Scandinavica
ISSN: 1600-0404
Pages:

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Medical and Biotech [MESH] Definitions

Epileptic condition in which adequate trials of two tolerated and appropriately chosen and used ANTIEPILEPTIC DRUGS schedules to achieve sustained seizure freedom failed.

A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.

Compounds and drugs that inhibit or block the activity of CATECHOL O-METHYLTRANSFERASE enzymes. Drugs in this class are used in management of central nervous system disorders such as PARKINSON DISEASE.

The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.

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