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Progranulin in the hematopoietic compartment protects mice from atherosclerosis.

08:00 EDT 30th August 2018 | BioPortfolio

Summary of "Progranulin in the hematopoietic compartment protects mice from atherosclerosis."

Progranulin is a circulating protein that modulates inflammation and is found in atherosclerotic lesions. Here we determined whether inflammatory cell-derived progranulin impacts atherosclerosis development.

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Journal Details

This article was published in the following journal.

Name: Atherosclerosis
ISSN: 1879-1484
Pages: 145-154

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Medical and Biotech [MESH] Definitions

Strains of mice that contain genetic disruptions (knockout) of APOLIPOPROTEINS E genes. They are used as models for ATHEROSCLEROSIS research.

Strains of mice arising from a parental inbred stock that was subsequently used to produce substrains of knockout and other mutant mice with targeted mutations.

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